A pilot study to evaluate micro-fragmented adipose tissue injection under ultrasound guidance for the treatment of refractory rotator cuff disease in wheelchair users with spinal cord injury

May 20, 2021

In this single group pilot study, a series of  10 wheel-chair users with chronic moderate-to severe shoulder pain caused by refractory rotator cuff disease received an ultra-sound guided intra-articular injection of Lipogems-derived micro-fragmented adipose tissue (MFAT) and were monitored for pain, adverse events and also by ultrasound over a 12 month period. The study showed that 80% of the patients saw a noticeable reduction in pain and an improvement in functional capability, whilst there were no adverse effects recorded. This indicates that MFAT injection maybe a medium-long-term effective remedy for the treatment of chronic rotator cuff shoulder injury and the authors are currently involved in a large randomised controlled clinical trial to test this hypothesis.​